Platform
Cellular Assays

Testing in proprietary and validated human primary
immortalized skin cells.

Flexible platform which customercan choose up to 25 targets and 31 end-points.

You can design your primary screening
and confirmatory assays.

Novel targets are always in development.

Key

Skin layer

  • EPIDERMIS

  • DERMIS

Activation process

  • Experimental model

Applicable scopes

  • Claim #1

  • Claim #2

  • Claim #3

  • Claim #4

  • EPIDERMIS

  •  

  • Proliferation and cytotoxicity in keratinocytes

  • Skin renewal

  • Skin barrier

  • EPIDERMIS

  •  

  • Wound healing
    in keratinocytes

  • Skin renewal

  • Skin barrier

  • EPIDERMIS

  •  

  • Nrf2 pathway in keratinocytes
    (activation and inhibition)

  • Skin renewal

  • Skin evenness

  • Anti-aging

  • Moisturizing

  • EPIDERMIS

  •  

  • NF-kB inflammation pathway
    in keratinocytes

  • Anti-aging

  • Skin defense

  • EPIDERMIS

  •  

  • Erythropoietin gene expression
    in keratinocytes

  • Skin renewal

  • Rejuvenation

  • Firming

  • EPIDERMIS

  •  

  • Mitogenesis
    in keratinocytes

  • Anti-aging

  • Skin defense

  • Moisturizing

  • EPIDERMIS

  •  

  • Cellular antioxidant and prooxidant activity
    in keratinocytes

  • Rejuvenation

  • Skin barrier

  • Anti-hyperpigmentation

  • Detox

  • EPIDERMIS

  •  

  • HMOX-1 gene transcription
    in Keratinocytes (induction)

  • Anti-aging

  • Skin barrier

  • Anti-inflammatory

  • Antioxidant

  • EPIDERMIS

  •  

  • UVB-induced senescence in keratinocytes

  • Skin renewal

  • Rejuvenation

  • Photoprotection

  • EPIDERMIS

  •  

  • Autophagy
    in keratinocytes

  • Skin renewal

  • Rejuvenation

  • Skin barrier

  • Anti-hyperpigmentation

  • EPIDERMIS

  •  

  • IL-31-induction activation
    in keratinocytes (inhibition)

  • Atopic and sensitive skin

  •  

  • DERMIS

  • Proliferation and cytotoxicity in fibroblasts

  • Skin renewal

  • Skin barrier

  •  

  • DERMIS

  • Wound healing
    in dermal fibroblasts

  • Skin renewal

  • Skin barrier

  • EPIDERMIS

  •  

  • Collagen gene expression
    in dermal fibroblasts

  • Rejuvenation

  • Firming

  • Anti-wrinkle

  • Tissue regeneration

  •  

  • DERMIS

  • NF-kB inflammation pathway in dermal fibroblasts

  • Skin renewal

  • Rejuvenation

  • Photoprotection

  • EPIDERMIS

  •  

  • Tyrosinase activity
    in human melanocytes

  • Anti-hyperpigmentation

  • EPIDERMIS

  •  

  • Melanin Synthesis
    in human melanocytes

  • Anti-hyperpigmentation

  • EPIDERMIS

  •  

  • Cyclic AMP signaling induction in human melanocytes (activation and inhibition)

  • Browning

  •  

  • DERMIS (Neuro)

  • CB1 signaling (activation and inhibition)

  • Atopic and sensitive skin

  • Itching

  • Soothing

  • Anti-inflammatory

  •  

  • DERMIS

  • CB2 signaling
    (activation)

  • Photoprotection

  • Anti-inflammatory

  •  

  • DERMIS (Neuro)

  • TRPV-1 signaling
    (activation and inhibition)

  • Rejuvenation

  • Anti-wrinkle

  • Atopic and sensitive skin

  • Soothing

  • EPIDERMIS

  •  

  • TGR5 signaling
    (activation and inhibition)

  • Hair loss

  • Atopic and sensitive skin

  • Itching

  • Soothing

  •  

  • DERMIS

  • WNT pathway in human primary dermal
    papilla cells

  • Hair loss

  • Soothing

  •  

  • DERMIS

  • NO synthesis in human dermal
    microvascular cells

  • Eye bags

  • Dark circles

  •  

  • DERMIS

  • HIF activation
    in dermal microvascular cells

  • Eye bags

  • Vascular spiders